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Molecular Ecology of Microbes
We have considerable expertise in using advanced molecular, computational and statistical techniques to investigate how consortia of eubacteria, archaea and eukaryotic microbes such as mycorhiza species adapt to their highly diverse environments. These range from woodland and field soils to the leaf surfaces of plants and from deepwater hypersaline marine environments to toxic shale-oil waste ponds.
Our facilities include:
- Cluster computing driven by powerful web-server workstations to allow efficient processing of large transcriptome datasets generated by next generation sequencing
- The availability of an Illumina MiSeq and associated equipment for massively parallel sequencing
- Gilson PipetMax automated liquid handling platform
- BluePippin nucleic acid/protein automated size selector for Next Generation Sequencing.
- Multiple multi-core bioinformatics servers dedicated solely to the analysis of microbial NGS data using all commonly available pipelines and custom analyses.
- NanoDrop 3000 Flurospectrometer – for picrogreen assays of very low concentration nucleic acid samples.
- Multiple standard and quantitative real-time thermocyclers, allowing the high-throughput processing of tens of thousands of samples.